The British lender has implemented CA Transaction Manager, which uses the 3-D Secure protocol with the Verified by Visa program to authenticate cardholders.
It has also deployed the CA Risk Analytics solution that helps evaluate the fraud risks of online transactions in real-time during the authentication process.
The solution assesses risk by analysing current and previous transactions, device characteristics, location, user behaviour and historical fraud data.
A purchase is allowed or rejected, or an alert is sent based on a risk score, which is calculated by assessing these parameters.
The technology provider said that prompt detection of legitimate transactions leads to better service experience, as well as also reduces operational costs.
Nationwide commercial manager Matthew Sparkes said: "CA Technologies plays a vital role in helping Nationwide deliver a frictionless eCommerce experience. By adding advanced analytics to the next generation of our digital verification process, 3-D Secure, Nationwide has the flexibility and control to make even the most complex transactions seamless and secure.
"CA's payment security solutions help us identify fraud more effectively, while improving the customer experience and delivering the insight we need to understand customers better and to drive business growth."